Glycoside constituents from Cayratia geniculata.
J Asian Nat Prod Res
; : 1-8, 2024 May 17.
Article
em En
| MEDLINE
| ID: mdl-38758006
ABSTRACT
Using various chromatographic separations, six glycoside derivatives (1-6), including one new ent-labdane glucoside named cayratioside (1), were isolated from the methanol extract of Cayratia geniculata stems and leaves. Their structures were elucidated by detailed analysis of the 1D, 2D NMR, and HRESIQTOF mass spectra. The inhibitory effect of 1-6 on LPS-induced NO production in RAW264.7 cells was also evaluated. Among isolated compounds, 1 exhibited moderate activity with an IC50 value of 59.65 ± 1.85 µM.
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MEDLINE
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En
Ano de publicação:
2024
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Article