Twenty-first century antiepileptic drugs. An overview of their targets and synthetic approaches.
Eur J Med Chem
; 272: 116476, 2024 Jun 05.
Article
em En
| MEDLINE
| ID: mdl-38759456
ABSTRACT
The therapeutic use of the traditional drugs against epilepsy has been hindered by their toxicity and low selectivity. These limitations have stimulated the design and development of new generations of antiepileptic drugs. This review explores the molecular targets and synthesis of the antiepileptic drugs that have entered the market in the 21st century, with a focus on manufacturer synthesis.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Epilepsia
/
Anticonvulsivantes
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article