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Rising tide: The global surge of type 2 diabetes in children and adolescents demands action now.
Pappachan, Joseph M; Fernandez, Cornelius James; Ashraf, Ambika P.
Afiliação
  • Pappachan JM; Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, Preston PR2 9HT, United Kingdom.
  • Fernandez CJ; Faculty of Science, Manchester Metropolitan University, Manchester M15 6BH, United Kingdom.
  • Ashraf AP; Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M13 9PL, United Kingdom. drpappachan@yahoo.co.in.
World J Diabetes ; 15(5): 797-809, 2024 May 15.
Article em En | MEDLINE | ID: mdl-38766426
ABSTRACT
Childhood-onset obesity has emerged as a major public healthcare challenge across the globe, fueled by an obesogenic environment and influenced by both genetic and epigenetic predispositions. This has led to an exponential rise in the incidence of type 2 diabetes mellitus in children and adolescents. The looming wave of diabetes-related complications in early adulthood is anticipated to strain the healthcare budgets in most countries. Unless there is a collective global effort to curb the devastation caused by the situation, the impact is poised to be pro-found. A multifaceted research effort, governmental legislation, and effective social action are crucial in attaining this goal. This article delves into the current epidemiological landscape, explores evidence concerning potential risks and consequences, delves into the pathobiology of childhood obesity, and discusses the latest evidence-based management strategies for diabesity.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article