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Potential application of munguba butter in the formulation of nanoemulsified systems.
Raiser, A L; Hoshino, T T; Torres, M P R; Debiasi, B W; Cotrim, A C M; Ribeiro, E B; Valladão, D M S.
Afiliação
  • Raiser AL; Universidade Federal do Mato Grosso - UFMT, Programa de Pós-graduação em Biotecnologia e Biodiversidade - PPGBB, Sinop, Sinop, MT, Brasil.
  • Hoshino TT; Universidade Federal do Mato Grosso - UFMT, Instituto de Ciências da Saúde, Sinop, Sinop, MT, Brasil.
  • Torres MPR; Universidade Federal do Mato Grosso - UFMT, Programa de Pós-graduação em Biotecnologia e Biodiversidade - PPGBB, Sinop, Sinop, MT, Brasil.
  • Debiasi BW; Universidade de São Paulo - USP, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - FCFRP, Programa de Pós-graduação em Ciências Farmacêuticas, Ribeirão Preto, SP, Brasil.
  • Cotrim ACM; Universidade Federal do Mato Grosso - UFMT, Barra do Garças, Barra do Garças, MT, Brasil.
  • Ribeiro EB; Universidade Federal do Mato Grosso - UFMT, Instituto de Ciências da Saúde, Sinop, Sinop, MT, Brasil.
  • Valladão DMS; Universidade Federal do Mato Grosso - UFMT, Programa de Pós-graduação em Biotecnologia e Biodiversidade - PPGBB, Sinop, Sinop, MT, Brasil.
Braz J Biol ; 84: e281236, 2024.
Article em En | MEDLINE | ID: mdl-38775525
ABSTRACT
Munguba butter has bioactive compounds such as vitamin E and phytosterols, which has valued its application in the development of new products, with advantages in its use in emulsified formulations. Therefore, the objective was to develop and evaluate the stability of a nanoemulsion containing munguba butter as the oily phase. Munguba butter was extracted by the ultrasound assisted method and its HLB (hydrophilic-lipophilic balance) was determined. Next, formulations varying the concentration of butter from 1-40% were developed and classified into liquid or solid emulsion and phase separation. Liquid emulsions were evaluated for hydrodynamic particle diameter, polydispersity index (PDI), Zeta potential (ζ), rheological characterization, and stability assays. The butter had an HLB of 6.98. The NE 1.0% formulation was selected and demonstrated to be unstable at high temperatures (45 ± 2 °C) and remained stable at room temperature, refrigeration and light radiation for 90 days. Munguba butter, because it has high amounts of saturated fatty acids, hinders its application in the development of new products. However, the success in the development of the NE 1.0% formulation is noteworthy, remaining stable when exposed to refrigeration, room temperature and light radiation.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Emulsões Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Emulsões Idioma: En Ano de publicação: 2024 Tipo de documento: Article