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Superior semicircular canal dehiscence postoperative outcomes: a case series of 350 repairs.
Mekonnen, Mahlet; Lum, Meachelle; Duong, Courtney; Rana, Shivam; Mozaffari, Khashayar; Hovis, Gabrielle E A; Yang, Isaac.
Afiliação
  • Mekonnen M; Department of Neurosurgery, University of California, Los Angeles, 300 Stein Plaza, Suite 562, Los Angeles, CA, 90095-1761, USA.
  • Lum M; Department of Neurosurgery, University of California, Los Angeles, 300 Stein Plaza, Suite 562, Los Angeles, CA, 90095-1761, USA.
  • Duong C; Department of Neurosurgery, University of California, Los Angeles, 300 Stein Plaza, Suite 562, Los Angeles, CA, 90095-1761, USA.
  • Rana S; Department of Neurosurgery, University of California, Los Angeles, 300 Stein Plaza, Suite 562, Los Angeles, CA, 90095-1761, USA.
  • Mozaffari K; Department of Neurosurgery, University of California, Los Angeles, 300 Stein Plaza, Suite 562, Los Angeles, CA, 90095-1761, USA.
  • Hovis GEA; Department of Neurosurgery, University of California, Los Angeles, 300 Stein Plaza, Suite 562, Los Angeles, CA, 90095-1761, USA.
  • Yang I; Department of Neurosurgery, University of California, Los Angeles, 300 Stein Plaza, Suite 562, Los Angeles, CA, 90095-1761, USA. iyang@mednet.ucla.edu.
Acta Neurochir (Wien) ; 166(1): 230, 2024 May 24.
Article em En | MEDLINE | ID: mdl-38789840
ABSTRACT

BACKGROUND:

Superior Semicircular Canal Dehiscence (SSCD) is a dehiscence of the otic capsule which normally lies over the superior semicircular canal. This database constitutes the largest series of SSCD patients to date.

OBJECTIVE:

To determine what preoperative factors, if any, contribute to postoperative outcomes and evaluate symptom resolution in a large SSCD patient cohort.

METHODS:

A single-institution, retrospective chart review collected patient demographics, intraoperative findings, and pre-and postoperative symptoms. Fisher's exact t-test was performed for unpaired categorical variables, with a significance level of p < 0.05.

RESULTS:

350 SSCD repairs were performed. The median age was 52 years (range 17-86 years, ± 6.4 years), and the median follow-up duration was 4.6 months (range 0.03-59.5 months, ± 6.8 months). Preoperative hearing loss was significantly associated with female sex (p = 0.0028). The most reported preoperative symptoms were tinnitus (77.4%), dizziness (74.0%), autophony (66.3%), amplification (63.7%), and disequilibrium (62.6%). Between patients who received unilateral versus bilateral SSCD repair, the greatest postoperative symptomatic resolution was seen in autophony (74.9%, p < 0.001), amplification (77.3%, p = 0.00027), hyperacusis (77.4%, p = 0.023), hearing (62.9%, p = 0.0063), and dizziness (54.6%, p < 0.001) for patients with unilateral SSCD repair.

CONCLUSION:

Surgical repair via the middle cranial fossa approach can significantly resolve auditory, vestibular, and neurological symptoms of patients with SSCD. Although this is one of the largest single-institution SSCD studies to date, future multi-institutional, prospective studies would be beneficial to validate these results.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deiscência do Canal Semicircular Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deiscência do Canal Semicircular Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article