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Advances in Nano-Functional Materials in Targeted Thrombolytic Drug Delivery.
Ren, Tengfei; Mi, Yuexi; Wei, Jingjing; Han, Xiangyuan; Zhang, Xingxiu; Zhu, Qian; Yue, Tong; Gao, Wenhao; Niu, Xudong; Han, Cuiyan; Wei, Bing.
Afiliação
  • Ren T; School of Basic Medical Sciences, Qiqihar Medical University, Qiqihar 161006, China.
  • Mi Y; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
  • Wei J; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
  • Han X; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
  • Zhang X; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
  • Zhu Q; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
  • Yue T; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
  • Gao W; School of Basic Medical Sciences, Qiqihar Medical University, Qiqihar 161006, China.
  • Niu X; School of Basic Medical Sciences, Qiqihar Medical University, Qiqihar 161006, China.
  • Han C; School of Basic Medical Sciences, Qiqihar Medical University, Qiqihar 161006, China.
  • Wei B; School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Molecules ; 29(10)2024 May 15.
Article em En | MEDLINE | ID: mdl-38792186
ABSTRACT
Thrombotic disease has been listed as the third most fatal vascular disease in the world. After decades of development, clinical thrombolytic drugs still cannot avoid the occurrence of adverse reactions such as bleeding. A number of studies have shown that the application of various nano-functional materials in thrombus-targeted drug delivery, combined with external stimuli, such as magnetic, near-infrared light, ultrasound, etc., enrich the drugs in the thrombus site and use the properties of nano-functional materials for collaborative thrombolysis, which can effectively reduce adverse reactions such as bleeding and improve thrombolysis efficiency. In this paper, the research progress of organic nanomaterials, inorganic nanomaterials, and biomimetic nanomaterials for drug delivery is briefly reviewed.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Sistemas de Liberação de Medicamentos / Fibrinolíticos Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Sistemas de Liberação de Medicamentos / Fibrinolíticos Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article