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Simplifying Data Analysis in Biomedical Research: An Automated, User-Friendly Tool.
Araújo, Rúben; Ramalhete, Luís; Viegas, Ana; Von Rekowski, Cristiana P; Fonseca, Tiago A H; Calado, Cecília R C; Bento, Luís.
Afiliação
  • Araújo R; NMS-NOVA Medical School, FCM-Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisbon, Portugal.
  • Ramalhete L; CHRC-Comprehensive Health Research Centre, Universidade NOVA de Lisboa, 1150-082 Lisbon, Portugal.
  • Viegas A; ISEL-Instituto Superior de Engenharia de Lisboa, Instituto Politécnico de Lisboa, Rua Conselheiro Emídio Navarro 1, 1959-007 Lisbon, Portugal.
  • Von Rekowski CP; NMS-NOVA Medical School, FCM-Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisbon, Portugal.
  • Fonseca TAH; Blood and Transplantation Center of Lisbon, IPST-Instituto Português do Sangue e da Transplantação, Alameda das Linhas de Torres 117, 1769-001 Lisbon, Portugal.
  • Calado CRC; iNOVA4Health-Advancing Precision Medicine, RG11: Reno-Vascular Diseases Group, NMS-NOVA Medical School, FCM-Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.
  • Bento L; CHRC-Comprehensive Health Research Centre, Universidade NOVA de Lisboa, 1150-082 Lisbon, Portugal.
Methods Protoc ; 7(3)2024 Apr 24.
Article em En | MEDLINE | ID: mdl-38804330
ABSTRACT
Robust data normalization and analysis are pivotal in biomedical research to ensure that observed differences in populations are directly attributable to the target variable, rather than disparities between control and study groups. ArsHive addresses this challenge using advanced algorithms to normalize populations (e.g., control and study groups) and perform statistical evaluations between demographic, clinical, and other variables within biomedical datasets, resulting in more balanced and unbiased analyses. The tool's functionality extends to comprehensive data reporting, which elucidates the effects of data processing, while maintaining dataset integrity. Additionally, ArsHive is complemented by A.D.A. (Autonomous Digital Assistant), which employs OpenAI's GPT-4 model to assist researchers with inquiries, enhancing the decision-making process. In this proof-of-concept study, we tested ArsHive on three different datasets derived from proprietary data, demonstrating its effectiveness in managing complex clinical and therapeutic information and highlighting its versatility for diverse research fields.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article