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Neutral rhodol-based dyes expressing localization in mitochondria.
Ferraboschi, Ilaria; Ovcar, Juraj; Vygranenko, Kateryna V; Yu, Shupei; Minervino, Alfonso; Wrzosek, Antoni; Szewczyk, Adam; Rozza, Riccardo; Magistrato, Alessandra; Belfield, Kevin D; Gryko, Daniel T; Grisanti, Luca; Sissa, Cristina.
Afiliação
  • Ferraboschi I; Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy. cristina.sissa@unipr.it.
  • Ovcar J; Ruder Boskovic Institute, Bijenicka cesta 54, 10000 Zagreb, Croatia. grisanti@iom.cnr.it.
  • Vygranenko KV; National Research Council - Materials Foundry Institute (CNR-IOM) c/o SISSA (International School for Advanced Studies), Via Bonomea 265, 34136 Trieste, Italy.
  • Yu S; Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
  • Minervino A; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey 07102, USA.
  • Wrzosek A; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey 07102, USA.
  • Szewczyk A; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Pasteura 3, 02-093 Warsaw, Poland.
  • Rozza R; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Pasteura 3, 02-093 Warsaw, Poland.
  • Magistrato A; National Research Council - Materials Foundry Institute (CNR-IOM) c/o SISSA (International School for Advanced Studies), Via Bonomea 265, 34136 Trieste, Italy.
  • Belfield KD; National Research Council - Materials Foundry Institute (CNR-IOM) c/o SISSA (International School for Advanced Studies), Via Bonomea 265, 34136 Trieste, Italy.
  • Gryko DT; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey 07102, USA.
  • Grisanti L; Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
  • Sissa C; Ruder Boskovic Institute, Bijenicka cesta 54, 10000 Zagreb, Croatia. grisanti@iom.cnr.it.
Org Biomol Chem ; 22(29): 5886-5890, 2024 07 24.
Article em En | MEDLINE | ID: mdl-38804835
ABSTRACT
Neutral rhodol-based red emitters are shown to efficiently localize in mitochondria, as demonstrated by confocal microscopy and co-localization studies. A simple model is proposed to explain the localization mechanism of neutral molecules. The model takes into account the strong coupling between the molecular dipole moment and the electric field of the inner mitochondrial membrane.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article