Time to full enteral feeding and its predictors among very low birth weight (VLBW) neonates admitted to the neonatal intensive care units (NICU) in comprehensive specialized hospitals in Northwest Ethiopia.
BMC Pediatr
; 24(1): 366, 2024 May 28.
Article
em En
| MEDLINE
| ID: mdl-38807061
ABSTRACT
BACKGROUND:
Time to full enteral feeding is the time when neonates start to receive all of their prescribed nutrition as milk feeds. Delayed to achieve full enteral feeding had resulted in short- and long-term physical and neurological sequelae. However, there are limited studies to assess the time to full enteral feeding and its predictors among very low birth-weight neonates in Ethiopia. Therefore, this study aimed to assess the time to full enteral feeding and its predictors among very low birth-weight neonates admitted to comprehensive specialized hospitals in Northwest Ethiopia.METHODS:
A multi-center institutional-based retrospective follow-up study was conducted among 409 VLBW neonates from March 1, 2019 to February 30, 2023. A simple random sampling method was used to select study participants. Data were entered into EpiData version 4.2 and then exported into STATA version 16 for analysis. The Kaplan-Meier survival curve together with the log-rank test was fitted to test for the presence of differences among groups. Proportional hazard assumptions were checked using a global test. Variables having a p- value < 0.25 in the bivariable Cox-proportional hazard model were candidates for multivariable analysis. An adjusted Hazard Ratio (AHR) with 95% Confidence Intervals (CI) was computed to report the strength of association, and variables having a P-value < 0.05 at the 95% confidence interval were considered statistically significant predictor variables.RESULT:
The median time to full enteral feeding was 10 (CI 10-11) days. Very Low Birth-Weight (VLBW) neonates who received a formula feeding (AHR 0.71, 95% CI 0.53, 0.96), gestational age of 32-37 weeks (AHR 1.66, 95% CI 1.23, 2.23), without Necrotizing Enterocolitis (NEC) (AHR 2.16, 95% CI 1.65, 2.84), and single birth outcome (AHR 1.42, 95% CI 1.07, 1.88) were statistically significant variables with time to full enteral feeding. CONCLUSION ANDRECOMMENDATIONS:
This study found that the median time to full enteral feeding was high. Type of feeding, Necrotizing Enterocolitis (NEC), Gestational Age (GA) at birth, and birth outcome were predictor variables. Special attention and follow-up are needed for those VLBW neonates with NEC, had a GA of less than 32 weeks, and had multiple birth outcomes.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Unidades de Terapia Intensiva Neonatal
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Nutrição Enteral
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Recém-Nascido de muito Baixo Peso
Limite:
Female
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Humans
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Male
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Newborn
País como assunto:
Africa
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article