Iron-catalyzed decarboxylative radical addition to chiral azomethine imines upon visible light.
Chem Commun (Camb)
; 60(49): 6316-6319, 2024 Jun 13.
Article
em En
| MEDLINE
| ID: mdl-38819219
ABSTRACT
Herein, we disclose an eco-efficient redox-neutral iron-catalyzed decarboxylative radical addition to chiral azomethine imines upon visible light (427 nm) giving cyclic hydrazine derivatives with dr ranging from 82 18 to >96 4. This earth-abundant metal promoted sequence proceeds efficiently under ligand-free conditions based on a LMCT process and opens a route to new chiral heterocycles.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article