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Novel tropane analogues as Hsp90 inhibitors targeting colon cancer: Synthesis, biological estimation, and molecular docking study.
Almehmadi, Samar J; Sabour, Rehab; Kassem, Asmaa F; Abbas, Eman M H; Alsaedi, Amani M R; Farghaly, Thoraya A.
Afiliação
  • Almehmadi SJ; Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, Saudi Arabia.
  • Sabour R; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
  • Kassem AF; Chemistry Department, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-kharj, 11942, Saudi Arabia; Department of Chemistry of Natural and Microbial Products, National Research Centre, Cairo 12622, Egypt.
  • Abbas EMH; Department of Chemistry of Natural and Microbial Products, National Research Centre, Cairo 12622, Egypt.
  • Alsaedi AMR; Department of Chemistry, Collage of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
  • Farghaly TA; Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, Saudi Arabia; Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt. Electronic address: thoraya-f@hotmail.com.
Bioorg Chem ; 150: 107497, 2024 Sep.
Article em En | MEDLINE | ID: mdl-38852311
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tropanos / Ensaios de Seleção de Medicamentos Antitumorais / Neoplasias do Colo / Proteínas de Choque Térmico HSP90 / Simulação de Acoplamento Molecular / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tropanos / Ensaios de Seleção de Medicamentos Antitumorais / Neoplasias do Colo / Proteínas de Choque Térmico HSP90 / Simulação de Acoplamento Molecular / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article