Individual treatment selection for patients with post-traumatic stress disorder: External validation of a personalised advantage index.

Tait, James; Kellett, Stephen; Saxon, David; Deisenhofer, Anne-Katharina; Lutz, Wolfgang; Barkham, Michael; Delgadillo, Jaime

Tait, James; Kellett, Stephen; Saxon, David; Deisenhofer, Anne-Katharina; Lutz, Wolfgang; Barkham, Michael; Delgadillo, Jaime.

Afiliação

Tait J; School of Psychology, University of Sheffield, ICOSS Building, 219 Portobello, Sheffield, S1 4DP, United Kingdom.
Kellett S; Grounded Research, RDaSH NHS Foundation Trust, Doncaster, United Kingdom.
Saxon D; Clinical and Applied Psychology Unit, School of Psychology, University of Sheffield, Sheffield, United Kingdom.
Deisenhofer AK; Clinical Psychology and Psychotherapy, Department of Psychology, University of Trier, Trier, Germany.
Lutz W; Clinical Psychology and Psychotherapy, Department of Psychology, University of Trier, Trier, Germany.
Barkham M; Clinical and Applied Psychology Unit, School of Psychology, University of Sheffield, Sheffield, United Kingdom.
Delgadillo J; Clinical and Applied Psychology Unit, School of Psychology, University of Sheffield, Sheffield, United Kingdom.

Psychother Res ; : 1-14, 2024 Jun 11.

Article em En | MEDLINE | ID: mdl-38862129

ABSTRACT

ABSTRACT

OBJECTIVE:

To test the predictive accuracy and generalisability of a personalised advantage index (PAI) model designed to support treatment selection for Post-Traumatic Stress Disorder (PTSD).

METHOD:

A PAI model developed by Deisenhofer et al. (2018) was used to predict treatment outcomes in a statistically independent dataset including archival records for N = 152 patients with PSTD who accessed either trauma-focussed cognitive behavioural therapy or eye movement desensitisation and reprocessing in routine care. Outcomes were compared between patients who received their PAI-indicated optimal treatment versus those who received their suboptimal treatment.

RESULTS:

The model did not yield treatment specific predictions and patients who had received their PAI-indicated optimal treatment did not have better treatment outcomes in this external validation sample.