Systematic review and meta-analysis of interventions to promote medication adherence among children, adolescents, and young adults with medical conditions.
J Pediatr Psychol
; 2024 Jun 21.
Article
em En
| MEDLINE
| ID: mdl-38905019
ABSTRACT
OBJECTIVE:
This meta-analysis examined the efficacy of adherence-promotion interventions for children, adolescents, and young adults prescribed a medication for > 90 days as part of a treatment regimen for a medical condition.METHODS:
A systematic literature review was conducted to identify randomized controlled trials of adherence-promotion interventions published between 2013 and 2023 and including children, adolescents, and/or young adults with a medical condition. A total of 38 articles representing 39 trials met inclusion criteria. A narrative synthesis was conducted to summarize included trials and a random-effects model was used to compute an overall intervention effect. Effect sizes by adherence outcome assessment methodology, participant age, and technology use were also computed.RESULTS:
Pediatric adherence-promotion interventions demonstrate a medium effect with those randomized to an intervention displaying greater improvements in medication adherence than those randomized to a comparator condition (SMD = 0.46, 95% CI 0.31, 0.60, n = 37; 95% Prediction Interval -0.32, 1.23).CONCLUSIONS:
Adherence interventions for children, adolescents, and young adults with medical conditions increase adherence.
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MEDLINE
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En
Ano de publicação:
2024
Tipo de documento:
Article