Curvature-induced clustering of cell adhesion proteins.
Phys Rev E
; 109(5-1): 054406, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38907394
ABSTRACT
Cell adhesion proteins typically form stable clusters that anchor the cell membrane to its environment. Several works have suggested that cell membrane protein clusters can emerge from a local feedback between the membrane curvature and the density of proteins. Here, we investigate the effect of such a curvature-sensing mechanism in the context of cell adhesion proteins. We show how clustering emerges in an intermediate range of adhesion and curvature-sensing strengths. We identify key differences with the tilt-induced gradient sensing mechanism we previously proposed (Lin et al., arXiv2307.03670).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Adesão Celular
/
Membrana Celular
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article