A HIF-2&#945;-dependent <i>KMT2E-AS1</i>/KMT2E axis orchestrates endothelial epigenetic and metabolic dysfunction in pulmonary hypertension.

A HIF-2α-dependent KMT2E-AS1/KMT2E axis orchestrates endothelial epigenetic and metabolic dysfunction in pulmonary hypertension.

Lemay, Sarah-Eve; Provencher, Steeve; Bonnet, Sébastien; Potus, François; Boucherat, Olivier.

Afiliação

Lemay SE; Pulmonary Hypertension Research Group, Québec Heart and Lung Institute Research Centre, Québec City, QC, Canada.
Provencher S; Pulmonary Hypertension Research Group, Québec Heart and Lung Institute Research Centre, Québec City, QC, Canada.
Bonnet S; Department of Medicine, Laval University, Québec City, QC, Canada.
Potus F; Pulmonary Hypertension Research Group, Québec Heart and Lung Institute Research Centre, Québec City, QC, Canada.
Boucherat O; Department of Medicine, Laval University, Québec City, QC, Canada.

Ann Transl Med ; 12(3): 55, 2024 Jun 10.

Article em En | MEDLINE | ID: mdl-38911559