The role of histology on the outcome of sinonasal carcinomas treated with radiotherapy: a single institution experience.

Kazemian, Ali; Farazmand, Borna; Taherioun, Maryam; Razmkhah, Mahdie; Shirkhoda, Mohammad; Jalaeefar, Amirmohsen; Garajei, Ata; Jafari, Mehrdad; Heidari, Farrokh; Aghili, Mahdi; Ghalehtaki, Reza

Kazemian, Ali; Farazmand, Borna; Taherioun, Maryam; Razmkhah, Mahdie; Shirkhoda, Mohammad; Jalaeefar, Amirmohsen; Garajei, Ata; Jafari, Mehrdad; Heidari, Farrokh; Aghili, Mahdi; Ghalehtaki, Reza.

Afiliação

Kazemian A; Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Farazmand B; Radiation Oncology Research Center, Cancer Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Taherioun M; Radiation Oncology Research Center, Cancer Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Razmkhah M; Department of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Shirkhoda M; Department of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Jalaeefar A; Department of Oncosurgery, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Garajei A; Department of Oncosurgery, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Jafari M; Department of Head and Neck Surgical Oncology and Reconstructive Surgery, Cancer Institute, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Heidari F; Department of Oral and Maxillofacial Surgery, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Aghili M; Department of Oto-Rhino-Laryngology and Head and Neck Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Ghalehtaki R; Department of Oto-Rhino-Laryngology and Head and Neck Surgery, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Radiat Oncol J ; 42(2): 116-123, 2024 Jun.

Article em En | MEDLINE | ID: mdl-38946073

ABSTRACT

ABSTRACT

PURPOSE:

Sinonasal malignancies are a rare group of head and neck cancers. We aimed to report the oncological outcomes based on histological types in patients who underwent radiotherapy. MATERIALS AND

METHODS:

In this single-institution study, we retrospectively retrieved and analyzed data of patients with sinonasal carcinomas who underwent radiotherapy during 2011-2016 as part of their treatment. The 3-year rate of local, regional, and distant recurrences, and overall survival were evaluated according to the histological type.

RESULTS:

A total of 28 patients were evaluated in this study, the majority of whom were male (60%). Squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and adenocarcinoma (ADC) were found in 15 patients (53.5%), 8 (28.5%), and 5 (18%), respectively. The highest rates of local and regional recurrences were observed in ACC and SCC, respectively. Distant recurrences were numerically more common in ADC. The 3-year OS was 48%, 50%, and 73% in SCC, ADC, and ACC, respectively.