Collapsing Glomerulopathy Leading To Rapidly Progressive Allograft Failure From Cytomegalovirus and SARS-CoV-2 Infection With Concomitant BK Virus Nephropathy.
Exp Clin Transplant
; 22(5): 392-395, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38970283
ABSTRACT
We present a challenging clinical case of a 68-year-old female kidney transplant recipient who had a complicated posttransplant course marked by borderline T-cell-mediated rejection and BK virus nephropathy. The treatment for borderline rejection with steroids resulted in overimmunosuppression, and the patient acquired cytomegalovirus infection manifesting as colitis and SARS-CoV-2 infection. This progressed rapidly to collapsing glomerulopathy and allograft failure. This study also highlights the challenges in surveillance with donor-derived cell-free DNA in the setting of allograft injury by multiple viral infections.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Tumorais por Vírus
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Transplante de Rim
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Vírus BK
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Infecções por Citomegalovirus
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Infecções por Polyomavirus
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COVID-19
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Rejeição de Enxerto
Limite:
Aged
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Female
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Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article