Biphasic co-detection of melanoma aneuploid tumor cells and tumor endothelial cells in guidance of specifying the field cancerized surgical excision margin and administering immunotherapy.

Fu, Zhengzheng; Zhang, Lina; Chen, Rongyi; Zhan, Jipang; Zhong, Jing; Zheng, Wen; Zou, Jingwen; Wang, Peng; Deng, Xiaohua; Lin, Alexander Y; Wang, Daisy Dandan; Lin, Peter Ping; He, Renliang

Fu, Zhengzheng; Zhang, Lina; Chen, Rongyi; Zhan, Jipang; Zhong, Jing; Zheng, Wen; Zou, Jingwen; Wang, Peng; Deng, Xiaohua; Lin, Alexander Y; Wang, Daisy Dandan; Lin, Peter Ping; He, Renliang.

Afiliação

Fu Z; Department of Dermatologic Surgery and Dermatologic Oncology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Zhang L; Department of Cellular and Molecular Biology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Chen R; Division of Cutaneous Oncology, Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Zhan J; Department of Dermatologic Surgery and Dermatologic Oncology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Zhong J; Department of Dermatologic Surgery and Dermatologic Oncology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Zheng W; Department of Dermatologic Surgery and Dermatologic Oncology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Zou J; Department of Dermatologic Surgery and Dermatologic Oncology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Wang P; Department of Pathology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Deng X; Department of Pathology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China.
Lin AY; Cytelligen, San Diego, CA, USA.
Wang DD; Cytelligen, San Diego, CA, USA.
Lin PP; Cytelligen, San Diego, CA, USA. Electronic address: plin@cytelligen.com.
He R; Department of Dermatologic Surgery and Dermatologic Oncology, Dermatology Hospital of Southern Medical University, Guangdong Provincial Dermatology Hospital, Guangzhou, China. Electronic address: zshrl2006@smu.edu.cn.

Cancer Lett ; 598: 217099, 2024 Aug 28.

Article em En | MEDLINE | ID: mdl-38971491

Assuntos

Aneuploidia; Células Endoteliais; Margens de Excisão; Melanoma; Humanos; Melanoma/patologia; Melanoma/imunologia; Melanoma/genética; Melanoma/terapia; Células Endoteliais/patologia; Células Endoteliais/metabolismo; Imunoterapia/métodos; Antígeno B7-H1/metabolismo; Antígeno B7-H1/genética; Células Neoplásicas Circulantes/patologia; Células Neoplásicas Circulantes/metabolismo; Hibridização in Situ Fluorescente; Masculino; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Neoplasias Cutâneas/patologia; Neoplasias Cutâneas/imunologia; Neoplasias Cutâneas/genética; Neoplasias Cutâneas/terapia; Pessoa de Meia-Idade; Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo; Molécula-1 de Adesão Celular Endotelial a Plaquetas/genética; Feminino

Palavras-chave

Aneuploid CTCs and CTECs; Cellular MRD; Quantified field cancerization; Safety excision margin; iFISH tumor tissue and liquid biopsies

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Endoteliais / Margens de Excisão / Aneuploidia / Melanoma Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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