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Assessing the efficacy of mesotherapy products: Ultra Exo Booster, and Ultra S Line Plus in hair growth: An ex vivo study.
Zhou, Shu Yi; Giang, Nguyen Ngan; Kim, Hyunjee; Chien, Pham Ngoc; Le, Linh Thi Thuy; Trinh, Thuy-Tien Thi; Nga, Pham Thi; Kwon, Han Jin; Ham, Jung Ryul; Lee, Won Ku; Gu, Yeon Ju; Zhang, Xin Rui; Jin, Yong Xun; Nam, Sun Young; Heo, Chan Yeong.
Afiliação
  • Zhou SY; Department of Medicine, College of Medicine, Seoul National University, Seoul, South Korea.
  • Giang NN; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
  • Kim H; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
  • Chien PN; Department of Medical Device Development, College of Medicine, Seoul National University, Seoul, South Korea.
  • Le LTT; Korean Institute of Nonclinical Study, H&Bio. Co. Ltd., Seongnam, South Korea.
  • Trinh TT; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
  • Nga PT; Korean Institute of Nonclinical Study, H&Bio. Co. Ltd., Seongnam, South Korea.
  • Kwon HJ; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
  • Ham JR; Department of Biomedical Science, College of Medicine, Seoul National University, Seoul, South Korea.
  • Lee WK; Faculty of Medical Technique, Hai Phong University of Medicine and Pharmacy, Haiphong, Vietnam.
  • Gu YJ; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
  • Zhang XR; Korean Institute of Nonclinical Study, H&Bio. Co. Ltd., Seongnam, South Korea.
  • Jin YX; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
  • Nam SY; Korean Institute of Nonclinical Study, H&Bio. Co. Ltd., Seongnam, South Korea.
  • Heo CY; UltraV Co., Ltd. R&D Center, Seoul, South Korea.
Skin Res Technol ; 30(7): e13780, 2024 Jul.
Article em En | MEDLINE | ID: mdl-39031929
ABSTRACT
In this study, scalp tissues from Korean adults between 20 and 80 without skin disease were used. Scalp tissues were processed, and hair follicles were isolated and cultured with different treatments (including Bioscalp, Ultra Exo Booster, and Ultra S Line Plus) from Ultra V company. Over 12 days, observations and measurements of hair follicle characteristics were recorded at intervals (Days 0, 3, 6, 9, and 12). The study assessed the impact of these substances on hair follicle growth and morphology. Bioscalp, combined with Ultra Exo Booster and Ultra S Line Plus, showed significant hair elongation in ex vivo. Preservation of hair bulb diameter was observed, indicating potential for sustained hair growth by exosome-based products. The hair growth cycle analysis suggested a lower transition to the catagen stage in test products from Ultra V compared to non-treated groups. The research findings indicated that the tested formulations, especially the combination of Bioscalp, Ultra Exo Booster, and Ultra S Line Plus, demonstrated significant effectiveness in promoting hair growth, maintaining the integrity of the hair bulb, and reducing the transition to the catagen stage. The study suggests promising alternative treatments for hair loss, illustrating results that were as good as those of the conventional testing product groups.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Couro Cabeludo / Folículo Piloso / Mesoterapia / Cabelo Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Couro Cabeludo / Folículo Piloso / Mesoterapia / Cabelo Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article