RNase R vs. PNPase: selecting the best-suited exoribonuclease for environmental adaptation.
Extremophiles
; 28(3): 35, 2024 Jul 25.
Article
em En
| MEDLINE
| ID: mdl-39052080
ABSTRACT
3' â 5' exoribonucleases play a critical role in many aspects of RNA metabolism. RNase R, PNPase, and RNase II are the major contributors to RNA processing, maturation, and quality control in bacteria. Bacteria don't seem to have dedicated RNA degradation machineries to process different classes of RNAs. Under different environmental and physiological conditions, their roles can be redundant and sometimes overlapping. Here, I discuss why PNPase and RNase R may have switched their physiological roles in some bacterial species to adapt to environmental conditions, despite being biochemically distinct exoribonucleases.
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Base de dados:
MEDLINE
Assunto principal:
Adaptação Fisiológica
/
Exorribonucleases
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article