Geriatric Nutritional Risk Index and 30-Day Postoperative Mortality in Geriatric Burn Patients.
J Surg Res
; 301: 610-617, 2024 Sep.
Article
em En
| MEDLINE
| ID: mdl-39094519
ABSTRACT
INTRODUCTION:
The geriatric nutritional risk index (GNRI) can easily identify malnutrition-associated morbidity and mortality. We investigated the association between preoperative GNRI and 30-d mortality in geriatric burn patients who underwent surgery.METHODS:
The study involved geriatric burn patients (aged ≥ 65 y) who underwent burn surgery between 2012 and 2022. The GNRI was computed using the following formula 1.489 × serum albumin concentration (mg/L) + 41.7 × patient body weight/ideal body weight. Patients were dichotomized into the high GNRI (≥ 82) and low GNRI (< 82) groups. GNRI was evaluated as an independent predictor of 30-d postoperative mortality. The study also evaluated the association between GNRI and sepsis, the need for continuous renal replacement therapy (CRRT), major adverse cardiac events (MACE), and pneumonia.RESULTS:
Out of 270 patients, 128 (47.4%) had low GNRI (< 82). Multivariate Cox regression analysis revealed that low GNRI was significantly associated with 30-d postoperative mortality (hazard ratio 1.874, 95% confidence interval [CI] 1.146-3.066, P = 0.001). Kaplan-Meier analysis revealed that the 30-day mortality rate differed significantly between the low and high GNRI groups (log-rank test, P < 0.001). The 30-d postoperative mortality (hazard ratio 2.677, 95% CI 1.536-4.667, P < 0.001) and the incidence of sepsis (odds ratio [OR] 2.137, 95% CI 1.307-3.494, P = 0.004), need for CRRT (OR 1.919, 95% CI 1.101-3.344, P = 0.025), MACE (OR 1.680, 95% CI 1.018-2.773, P = 0.043), and pneumonia (OR 1.678, 95% CI 1.019-2.764, P = 0.044), were significantly higher in the low GNRI group than in the high GNRI group.CONCLUSIONS:
Preoperative low GNRI was associated with increased 30-d postoperative mortality, sepsis, need for CRRT, MACE, and pneumonia in geriatric burn patients.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
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Queimaduras
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Avaliação Geriátrica
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Avaliação Nutricional
Limite:
Aged
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Aged80
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article