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Hydrogel mechanical properties in altered gravity.
Miskovic, Vanja; Greco, Immacolata; Minetti, Christophe; Cialdai, Francesca; Monici, Monica; Gazzi, Arianna; Marcellino, Jeremiah; Samad, Yarjan Abdul; Delogu, Lucia Gemma; Ferrari, Andrea C; Iorio, Carlo Saverio.
Afiliação
  • Miskovic V; Centre for Research and Engineering in Space Technologies, École Polytechnique de Bruxelles, Université libre de Bruxelles, Brussels, Belgium.
  • Greco I; Centre for Research and Engineering in Space Technologies, École Polytechnique de Bruxelles, Université libre de Bruxelles, Brussels, Belgium.
  • Minetti C; Centre for Research and Engineering in Space Technologies, École Polytechnique de Bruxelles, Université libre de Bruxelles, Brussels, Belgium.
  • Cialdai F; ASAcampus Joint Laboratory, ASA Research Division, Department of Experimental and Clinical Biomedical Sciences « Mario Serio ¼, University of Florence, Florence, Italy.
  • Monici M; ASAcampus Joint Laboratory, ASA Research Division, Department of Experimental and Clinical Biomedical Sciences « Mario Serio ¼, University of Florence, Florence, Italy.
  • Gazzi A; Department of Chemical and Pharmaceutical Sciences, University of Trieste, Trieste, Italy.
  • Marcellino J; Department of Biomedical Sciences, University of Padua, Padua, Italy.
  • Samad YA; Cambridge Graphene Centre, University of Cambridge, Cambridge, CB3 0FA, UK.
  • Delogu LG; Cambridge Graphene Centre, University of Cambridge, Cambridge, CB3 0FA, UK.
  • Ferrari AC; Department of Aerospace Engineering, Khalifa university of Science and Technology, Abu Dhabi, 127788, UAE.
  • Iorio CS; Department of Biomedical Sciences, University of Padua, Padua, Italy.
NPJ Microgravity ; 10(1): 83, 2024 Aug 08.
Article em En | MEDLINE | ID: mdl-39117674
ABSTRACT
Exposure to altered gravity influences cellular behaviour in cell cultures. Hydrogels are amongst the most common materials used to produce tissue-engineering scaffolds, and their mechanical properties play a crucial role in cell-matrix interaction. However, little is known about the influence of altered gravity on hydrogel properties. Here we study the mechanical properties of Poly (ethylene glycol) diacrylate (PEGDA) and PEGDA incorporated with graphene oxide (GO) by performing tensile tests in micro and hypergravity during a Parabolic flight campaign, and by comparing them to the same tests performed in Earth gravity. We show that gravity levels do not result in a statistically significant difference in Young's modulus.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article