Effect of honey and povidone-iodine on acute laceration wound healing: a pilot randomised controlled trial study.
J Wound Care
; 33(8): 570-576, 2024 Aug 02.
Article
em En
| MEDLINE
| ID: mdl-39137253
ABSTRACT
OBJECTIVE:
Acute laceration wound (ALW) is one of the most common injuries in Indonesia with potential significant morbidities. In rural areas, povidone-iodine and honey are commonly used as wound dressings. This study aimed to identify the effectiveness of honey compared to paraffin gauze and the commonly used povidone-iodine in improving ALW healing time.METHOD:
This study was a single-blind, pilot randomised controlled trial (RCT) with three intervention groups (honey, povidone-iodine, and paraffin). The outcomes were wound healing time, slow healing, secondary healing, signs of infection, wound dehiscence, oedema, maceration, necrosis, exudate and cost.RESULTS:
A total of 35 patients (male to female ratio 41), with a mean age of 22.5 (range 6-47) years, were included and randomised to treatment groups using predetermined randomisation according to wound location and wound dressing selection honey group, n=12; povidone-iodine group, n=11; paraffin group, n=12 with one patient lost to follow-up. All groups achieved timely healing, with a mean healing time of 9.45±5.31 days and 11.09±5.14 days for the povidone-iodine and paraffin groups, respectively, and a median healing time of 10 (3-19) days for the honey group (p>0.05). More wounds in the honey group achieved healing in ≤10 days compared with the other groups. Both povidone-iodine and honey groups had fewer adverse events, with the latter having the lowest cost.CONCLUSION:
In this study, honey was clinically effective in accelerating healing time with a lower cost compared to paraffin, and was comparable to povidone-iodine. Future RCTs with a larger sample size should be pursued to determine honey's role in ALW treatment.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Povidona-Iodo
/
Cicatrização
/
Lacerações
/
Mel
/
Anti-Infecciosos Locais
Limite:
Adolescent
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Adult
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Child
/
Female
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Humans
/
Male
/
Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article