An analysis of the effect of low titer O whole blood (LTOWB) proportions for resuscitation after trauma on 6-hour and 24-hour survival.
Am J Surg
; 237: 115900, 2024 Nov.
Article
em En
| MEDLINE
| ID: mdl-39168048
ABSTRACT
INTRODUCTION:
Hemorrhage is a leading cause of death. Blood products are used for the treatment of hemorrhagic shock. The use of low titer group O whole blood (LTOWB) has become more common.METHODS:
Data from patients ≥15 years of age in the Trauma Quality Improvement Program (TQIP) database that received ≥10 units of packed red cells and/or LTOWB within the first 4-h of hospital arrival were included. The proportion of LTWOB of total blood products administered was correlated to 6- and 24-h mortality.RESULTS:
12,763 met inclusion, 3827 (30â¯%) received LTOWB. On multivariable logistic regression (MVLR), there was no difference in survival at 6â¯h with a LTOWB. When assessing 24-h survival, there was improved survival with LTOWB ≥10â¯% (OR 1.18, 1.08-1.28).CONCLUSIONS:
In this analysis of TQIP data, patients receiving ≥10 units of PRBC or LTOWB, we found that higher proportions of LTOWB transfusion relative to the total volume of blood products transfused during the first 4â¯h were associated with improved 24-h, but not 6-h survival.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Ressuscitação
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Choque Hemorrágico
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Ferimentos e Lesões
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Transfusão de Sangue
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Sistema ABO de Grupos Sanguíneos
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article