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Quality over quantity - rethinking social participation in dementia prevention: results from the AgeWell.de trial.
Kosilek, Robert P; Wendel, Flora; Zöllinger, Isabel; Knecht, Hanna Lea; Blotenberg, Iris; Weise, Solveig; Fankhänel, Thomas; Döhring, Juliane; Williamson, Martin; Luppa, Melanie; Zülke, Andrea E; Brettschneider, Christian; Wiese, Birgitt; Hoffmann, Wolfgang; Frese, Thomas; König, Hans-Helmut; Kaduszkiewicz, Hanna; Thyrian, Jochen René; Riedel-Heller, Steffi G; Gensichen, Jochen.
Afiliação
  • Kosilek RP; Institute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany. robert_philipp.kosilek@med.uni-muenchen.de.
  • Wendel F; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany. robert_philipp.kosilek@med.uni-muenchen.de.
  • Zöllinger I; Institute for Medical Information Processing, Biometry and Epidemiology (IBE), LMU Munich, Munich, Germany.
  • Knecht HL; Institute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany.
  • Blotenberg I; German Centre for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald, Greifswald, Germany.
  • Weise S; German Centre for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald, Greifswald, Germany.
  • Fankhänel T; Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
  • Döhring J; Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
  • Williamson M; Institute of General Practice, University of Kiel, Kiel, Germany.
  • Luppa M; Institute of General Practice, University of Kiel, Kiel, Germany.
  • Zülke AE; Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
  • Brettschneider C; Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
  • Wiese B; Department of Health Economics and Health Service Research, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Hoffmann W; Work Group Medical Statistics and IT-Infrastructure, Institute for General Practice, Hannover Medical School, Hannover, Germany.
  • Frese T; German Centre for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald, Greifswald, Germany.
  • König HH; Institute for Community Medicine, University Medicine Greifswald (UMG), Greifswald, Germany.
  • Kaduszkiewicz H; Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
  • Thyrian JR; Department of Health Economics and Health Service Research, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Riedel-Heller SG; Institute of General Practice, University of Kiel, Kiel, Germany.
  • Gensichen J; German Centre for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald, Greifswald, Germany.
Article em En | MEDLINE | ID: mdl-39251412
ABSTRACT

BACKGROUND:

Social participation as a protective factor against cognitive decline was one of the targets in the AgeWell.de study, a multi-domain interventional trial in a sample of older adults at increased risk for dementia. This study aimed to examine differential effects of the intervention and other influencing factors on social participation throughout the trial.

METHODS:

A longitudinal analysis of study data at the primary follow-up after 24 months (n = 819) was conducted. The Lubben Social Network Scale (LSNS-6) was used to assess quantitative aspects of social networks, and self-reported social activities were classified using a three-tiered categorical framework to capture qualitative aspects.

RESULTS:

A positive effect of the intervention was observed at the qualitative framework level, with an OR of 1.38 [95% CI 1.05-1.82] for achieving or maintaining higher social participation at follow-up, while no effect could be detected on quantitative social network characteristics. Later phases of the Covid-19 pandemic showed a negative impact on the level of social participation at follow-up with an OR of 0.84 [95% CI 0.75-0.95].

CONCLUSIONS:

These findings suggest that by focusing on qualitative aspects of social participation as a component of dementia prevention, future interventions can promote enriched social interactions within established social networks. TRIAL REGISTRATION German Clinical Trials Register (DRKS) ID DRKS00013555.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article