Safety of flurbiprofen in the treatment of ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis. A summary of liver and kidney assay data.
Am J Med
; 80(3A): 23-30, 1986 Mar 24.
Article
em En
| MEDLINE
| ID: mdl-3963024
ABSTRACT
The safety of flurbiprofen (Ansaid, Upjohn) was assessed after pooling data on kidney and liver function collected from nine separate phase III clinical trials involving 1,677 patients (941 receiving flurbiprofen and 736 receiving comparison drugs) with ankylosing spondylitis, osteoarthritis, or rheumatoid arthritis. Multiple categories were created to discern the effects of treatment, disease, age (under 60 and 60 years or older), and duration of exposure to flurbiprofen. No clinically significant trends in kidney or liver function were detected in any category following the administration of flurbiprofen.
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Base de dados:
MEDLINE
Assunto principal:
Osteoartrite
/
Artrite Reumatoide
/
Propionatos
/
Espondilite Anquilosante
/
Flurbiprofeno
Tipo de estudo:
Clinical_trials
Limite:
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
1986
Tipo de documento:
Article