Determination of the rate of urea synthesis from serial measurements of plasma urea concentration after an alanine load: theoretical and methodological aspects.
Clin Sci (Lond)
; 68(2): 201-8, 1985 Feb.
Article
em En
| MEDLINE
| ID: mdl-3967467
ABSTRACT
A method is described by which the rate of synthesis of urea can be calculated from the change of plasma concentration of urea after an alanine load. The results can be expressed in terms of f, the maximum increase in the rate of urea synthesis, and t, the time at which urea synthesis reaches its maximum. These parameters are calculated by an algebraic curve-fitting technique which is suitable for a desk computer. The method removes the need for isotopic analysis and urine collections. The effect of various errors and experimental conditions on the calculated synthesis parameters is investigated.
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Base de dados:
MEDLINE
Assunto principal:
Ureia
/
Alanina
/
Modelos Biológicos
Limite:
Humans
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article