A simple adult-mouse test for tissue invasiveness in Yersinia enterocolitica strains of low experimental virulence.
J Med Microbiol
; 19(2): 237-46, 1985 Apr.
Article
em En
| MEDLINE
| ID: mdl-3981611
ABSTRACT
The virulence of Yersinia enterocolitica depends on the presence of a 70-kilobase plasmid, called the Vwa plasmid. This situation is particularly favourable for studies of the mechanism of pathogenicity, but these are hindered by the lack of a suitable animal test to monitor the virulence of the human-pathogenic strains isolated outside the USA which belong to serogroups O3, O9 and O5,27. We observed that, after oral administration to the mouse, the Vwa-positive strains of these serogroups produce a discrete systemic infection while the Vwa-negative strains do not. We present here a simple mouse-virulence test based on this observation.
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Base de dados:
MEDLINE
Assunto principal:
Yersinia enterocolitica
Limite:
Animals
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article