Antiestrogenic therapy of meningiomas--a pilot study.
Surg Neurol
; 24(3): 245-9, 1985 Sep.
Article
em En
| MEDLINE
| ID: mdl-4023903
ABSTRACT
Six patients with inoperable, nonoperative, or recurrent meningiomas were treated with the antiestrogenic agent tamoxifen (Nolvadex) during an 8-12-month period. Computer tomographic, scintigraphic, and clinical evidence of an unspecific tumor response was only encountered in one patient after 4 months of therapy with tamoxifen. The 2-year results did not indicate a favorable response to antiestrogenic treatment. The significance of sex-steroid receptors and their possible prognostic value in endocrine therapy of meningiomas is discussed.
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Base de dados:
MEDLINE
Assunto principal:
Tamoxifeno
/
Neoplasias Meníngeas
/
Meningioma
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article