Cyclosporin A in the treatment of severe acute aplastic anaemia.
Br J Haematol
; 61(2): 267-72, 1985 Oct.
Article
em En
| MEDLINE
| ID: mdl-4041370
ABSTRACT
Twelve consecutive adults with severe acute aplastic anaemia, not having a bone marrow transplantation option, were prospectively randomized to receive either cyclosporin A alone or an equivalent amount of this immunosuppressive agent in combination with antilymphocyte serum. The minimum follow-up is 36 months, with half the patients developing nephrotoxicity, which was easily reversible in all but one. No response could be attributed to either regimen. Cyclosporin A does not appear to have a place as primary form of treatment for adults with severe acute aplastic anaemia, either on its own or in combination with antilymphocyte serum.
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Base de dados:
MEDLINE
Assunto principal:
Ciclosporinas
/
Anemia Aplástica
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article