Pronase effect on pancreatic beta cell secretion and morphology.
Science
; 180(4086): 647-9, 1973 May 11.
Article
em En
| MEDLINE
| ID: mdl-4573394
ABSTRACT
Pronase at low concentration (4 micrograms per milliliter) produces a reversible increase of glucose-stimulated insulin release in isolated islets of Langerhans. Pronase also affects the ultrastructure of the beta cells by inducing extensive development of tight junctions as well as the accumulation of secretory product within the extracellular spaces.
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Base de dados:
MEDLINE
Assunto principal:
Pronase
/
Ilhotas Pancreáticas
/
Insulina
Limite:
Animals
Idioma:
En
Ano de publicação:
1973
Tipo de documento:
Article