Use of antilymphocyte globulin after cadaveric renal transplantation.
Br Med J
; 4(5682): 522-5, 1969 Nov 29.
Article
em En
| MEDLINE
| ID: mdl-4901345
ABSTRACT
Antilymphocyte globulin (A.L.G.) was prepared by injecting fresh frozen splenic cells subcutaneously into horses. The IgG fraction of the serum was concentrated by a batch technique using diethylaminoethanol-Sephadex. Fourteen patients given this material by intramuscular injection after cadaveric renal transplants, in addition to azathioprine and prednisone, had less evidence of rejection compared with patients previously treated with azathioprine and prednisone only, despite a reduction of the mean daily prednisone dose from 65 to 45 mg. Toxicity, especially local reaction, fever, and hypotension, limited the amount of A.L.G. that was given.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
/
Soro Antilinfocitário
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1969
Tipo de documento:
Article