Conformational analysis of synthetic androgens. IV. 1,2-seco-a-bisnor-5 alpha-androstan-17 beta-ol acetate.
Steroids
; 34(5): 589-95, 1979 Nov.
Article
em En
| MEDLINE
| ID: mdl-516119
ABSTRACT
The crystal and molecular structure of 1,2-seco-A-bisnor-5 alpha-androstan-17beta-ol acetate has been determined to evaluated the conformational importance of the intact steroid nucleus. The resulting tricyclic compound retains nearly the same steric profile for the remainder of the molecule when compared to the structures of dihydrotestosterone derivatives with intact A-rings. This may help to explain why these types of molecules retain a significant level of androgenic activity.
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Base de dados:
MEDLINE
Assunto principal:
Congêneres da Testosterona
/
Androstanóis
Idioma:
En
Ano de publicação:
1979
Tipo de documento:
Article