Temporal relation between long-lasting aftercontractions and action potentials in cat papillary muscles.
Science
; 161(3838): 293-5, 1968 Jul 19.
Article
em En
| MEDLINE
| ID: mdl-5657338
ABSTRACT
Sotalol, an adrenergic-blocking and antiarrhythmic agent, increases markedly and simultaneously the duration of both action potentials and contractions in papillary muscles. The active tension is manifested as a main twitch contraction followed by a maintained low level of residual tension (aftercontraction) which persists until the terminal phase of rapid repolarization. The Strength of the aftercontraction is augmented when the extracellular concentration of calcium is increased.
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Base de dados:
MEDLINE
Assunto principal:
Simpatolíticos
/
Potenciais de Ação
/
Coração
/
Contração Muscular
Limite:
Animals
Idioma:
En
Ano de publicação:
1968
Tipo de documento:
Article