Hemicholinium-3: noncholinergic effects on squid axons.
Science
; 163(3869): 820-1, 1969 Feb 21.
Article
em En
| MEDLINE
| ID: mdl-5764476
ABSTRACT
Hemicholinium-3, when applied to the inside of a squid axon, is effective in blocking the action potential. This action is not antagonized by the addition of choline or acetylcholine to the perfusate. Voltage-clamp experiments show that hemicholinium-3 depresses both the early transient and late steady-state components of membrane ionic conductances, with a greater effect on the peak transient component.
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Base de dados:
MEDLINE
Assunto principal:
Parassimpatolíticos
/
Axônios
Limite:
Animals
Idioma:
En
Ano de publicação:
1969
Tipo de documento:
Article