Ionic mechanisms of cholinergic excitation in molluscan neurons.
Science
; 156(3782): 1597-9, 1967 Jun 23.
Article
em En
| MEDLINE
| ID: mdl-6025117
ABSTRACT
Acetylcholine appears to be an excitatory transmitter at synapses on two different types of molluscan nerve cells the so-called D- and CILDA neurons. The action of this substance is different in the two cases. In D-neurons, this compound increases the permeability of the subsynaptic or somatic membrane to chloride ions, and through a net efflux of this anion, depolarizes the cell. In CILDA neurons, on the other hand, acetylcholine depolarzies the cell by increasing its permeability to sodium ions.
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Base de dados:
MEDLINE
Assunto principal:
Sinapses
/
Acetilcolina
/
Cloretos
/
Eletrofisiologia
/
Neurônios
Limite:
Animals
Idioma:
En
Ano de publicação:
1967
Tipo de documento:
Article