[Activation of the complement system with clinical dextran (Macrodex 6%) in 10 patients in a cross-over design against 0,9%-NaCl]. / Untersuchung zur Aktivierung des Komplementsystems durch klinisches Dextran (Macrodex 6%) an 10 Probanden im Cross-over-Design gegen 0,9%-NaCl.
Infusionsther Klin Ernahr
; 7(5): 254-9, 1980 Oct.
Article
em De
| MEDLINE
| ID: mdl-6161897
ABSTRACT
The possibility of activation of the complement system with clinical Dextran 60 (500 ml Macrodex 6% infusion) as compaired with 500 ml 0.9% NaCl was investigated within a one week interval in 10 volunteers of both sexes in a cross-over design. Anaphylactoid symptoms, which would indicate a release of biological activities, were not induced by Dextran 60 or 0.9% NaCl. Neither could a change in blood pressure, heart rate, in the whole hemolytic complement activity nor in the leucocyte and thrombocyte count be determined. Therefore, a clinical relevant activation of the complement system in normal persons by Macrodex 6% can not be assumed.
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Base de dados:
MEDLINE
Assunto principal:
Cloreto de Sódio
/
Dextranos
/
Ativação do Complemento
Tipo de estudo:
Clinical_trials
Limite:
Female
/
Humans
/
Male
Idioma:
De
Ano de publicação:
1980
Tipo de documento:
Article