Release of immunoreactive serotonin into the lumen of the feline gut in response to vagal nerve stimulation.
Science
; 213(4513): 1254-5, 1981 Sep 11.
Article
em En
| MEDLINE
| ID: mdl-6168020
ABSTRACT
Immunoreactive serotonin was detected in the lumen of the proximal jejunum of food-deprived cats. During perfusion of this intestinal segment in vivo, there was a constant basal rate of intraluminal secretion of this amine. The rate of secretion was significantly increased during efferent electrical stimulation of the cut cervical vagal nerves. This stimulatory effect was not altered after bilateral adrenalectomy was performed in the same animals. A synchronous release of substance P into the gut lumen was also demonstrated during vagal stimulation. During the period of increased intraluminal secretion of immunoreactive serotonin, there was no demonstrable change in the portal or systemic blood levels of this amine.
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Base de dados:
MEDLINE
Assunto principal:
Nervo Vago
/
Serotonina
/
Sistema Cromafim
/
Células Enterocromafins
/
Jejuno
Limite:
Animals
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Article