Calcium phosphate crystal formation in Escherichia coli from human urine: an in vitro study.
J Urol
; 127(1): 184-5, 1982 Jan.
Article
em En
| MEDLINE
| ID: mdl-6276577
ABSTRACT
Escherichia coli with no demonstrable urease activity was inoculated into filter sterilized urine obtained from a healthy volunteer subject with no history of stone disease and then incubated at 37 degrees C. Bacteria were recovered at intervals between 1 and 10 days. Urinary pH was stable as compared to control urines and spontaneous crystal precipitation was not noted in controls. Recovered organisms were analyzed by x-ray powder diffractometry. An uncharacterized mineral phase (UMP) was first evident after 6 days. Calcium phosphate in the form of brushite and hydroxyapatite was apparent at 7 and 10 days respectively. This suggests a role for bacteria in calcium phosphate crystal formation in urine apart from urease activity and may contribute to the calcium phosphate component of urinary calculi.
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Base de dados:
MEDLINE
Assunto principal:
Fosfatos de Cálcio
/
Escherichia coli
Limite:
Humans
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article