Neuronal and astrocytic differentiation in human neuroepithelial neoplasms. An immunohistochemical study.
J Neuropathol Exp Neurol
; 42(2): 113-21, 1983 Mar.
Article
em En
| MEDLINE
| ID: mdl-6338157
ABSTRACT
Neuroepithelial neoplasms of childhood were examined immunohistochemically using antibodies against a neurofilament polypeptide and glial fibrillary acidic protein. Ninety-one cases, including 11 controls, were examined. Positively reacting cells, indicating neuronal and glial differentiation, were found in 59 of the 80 tumors. The study supports a neuroepithelial origin for medulloblastomas, central neuroblastomas, and primitive neuroectodermal tumors of childhood. The results also indicate that only a small number of the tumor cells differentiate along either neuronal or glial cell lines.
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Base de dados:
MEDLINE
Assunto principal:
Astrocitoma
/
Neoplasias Encefálicas
/
Tumores Neuroectodérmicos Primitivos Periféricos
Limite:
Child
/
Humans
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article