Prostacyclin infusion in acute cerebral infarction.
Neurology
; 34(11): 1431-5, 1984 Nov.
Article
em En
| MEDLINE
| ID: mdl-6387533
ABSTRACT
We gave prostacyclin infusions to seven patients with acute cerebral infarction. Patients without CT evidence of infarction improved, but those who already had hypodensities on CT did not benefit. Increased platelet activity, measured by plasma beta-thromboglobulin, decreased significantly (p less than 0.01) during prostacyclin administration to normal levels, but rose again after the infusion. These results indicate that prostacyclin can be given safely in doses adequate to suppress platelet function. Our findings encouraged us to proceed with a controlled trial of its clinical efficacy.
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Base de dados:
MEDLINE
Assunto principal:
Infarto Cerebral
/
Epoprostenol
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1984
Tipo de documento:
Article