Plasma immunoreactive beta-melanocyte-stimulating hormone in chronic liver disease and fulminant hepatic failure.
J Invest Dermatol
; 70(6): 326-7, 1978 Jun.
Article
em En
| MEDLINE
| ID: mdl-649979
ABSTRACT
Hyperpigmentation believed to be due to melanin, is a feature of chronic liver disease, especially primary biliary cirrhosis and hemochromatosis. Normal plasma concentrations of immunoreactive beta-melanocyte-stimulating hormone (beta-MSH) have been found in both these conditions; thus elevation of plasma beta-MSH plays no role in the pathogenesis of hepatic pigmentation. Normal levels are also found in hepatocellular failure, which supports the hypothesis that the kidney and not the liver is the site of metabolism of this hormone.
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Base de dados:
MEDLINE
Assunto principal:
Transtornos da Pigmentação
/
Hormônios Estimuladores de Melanócitos
/
Encefalopatia Hepática
/
Hemocromatose
/
Cirrose Hepática Biliar
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1978
Tipo de documento:
Article