A study of the possible role of mesothelium as a surface for flowing blood.
Thromb Haemost
; 51(1): 57-60, 1984 Feb 28.
Article
em En
| MEDLINE
| ID: mdl-6547010
ABSTRACT
Mouse mesothelium has been examined as a surface for supporting blood flow. We have examined ten pieces of intact mesothelium and ten pieces of damaged mesothelium following 10 min exposure to flowing blood in a Baumgartner chamber. Scanning electron microscopy of the intact specimens demonstrated no adhering blood platelets, whereas the damaged specimens were found to be covered with large numbers of adhering platelets. In addition we have demonstrated that undamaged mesothelium does not appear to be morphologically altered after exposure to blood, and that undamaged mesothelium produces significantly more prostacyclin than damaged control. These findings support that mesothelial cells hold promise as a lining for prosthetic vascular implants.
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Base de dados:
MEDLINE
Assunto principal:
Bioprótese
/
Vasos Sanguíneos
/
Epitélio
/
Hemodinâmica
Limite:
Humans
/
Male
Idioma:
En
Ano de publicação:
1984
Tipo de documento:
Article