Determinants of ovarian cancer risk. I. Reproductive experiences and family history.
J Natl Cancer Inst
; 71(4): 711-6, 1983 Oct.
Article
em En
| MEDLINE
| ID: mdl-6578366
ABSTRACT
Reproductive experiences and family history were assessed in 215 white females with epithelial ovarian cancer and in 215 control women matched by age, race, and residence. Pregnancy exerted a strong protective effect against ovarian cancer, which increased with the number of live-born children. After adjustment for parity, an effect of age at first live birth and breast-feeding was not apparent. Menstrual events did not differ significantly between cases and controls, although cases were more likely to have had an earlier menopause and less likely to have had a surgical menopause. Women with ovarian cancer had more frequently used menopausal hormones in cyclic fashion compared to controls. Regarding family history, women with ovarian cancer more frequently reported consanguinity in their ancestry and a highly frequency of primary relatives with cancer of the colon, lung, ovary, and prostate gland.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Gravidez
/
Métodos Epidemiológicos
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article