Suppression of prolactin by dopamine agonists in schizophrenics and controls.
Am J Psychiatry
; 135(8): 949-51, 1978 Aug.
Article
em En
| MEDLINE
| ID: mdl-665840
ABSTRACT
Prolactin levels were determined in plasma samples obtained before and after administration of apomorphine or L-dopa to otherwise unmedicated chronic schizophrenic patients or control subjects. Basal prolactin levels did not differ in these two groups. Suppression of prolactin levels after each dopamine agonist was highly significant. Suppression in schizophrenics was slightly less than in controls following apomorphine and slightly greater following L-dopa. The authors discuss the implications of these findings as well as the limitations of the prolactin regulatory system as an index of dopamine agonist sensitivity.
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Base de dados:
MEDLINE
Assunto principal:
Prolactina
/
Esquizofrenia
/
Apomorfina
/
Levodopa
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1978
Tipo de documento:
Article