[Effect of 1-(chloromethyl)silatrane on biochemical indices in the tissue of experimental gastric ulcer]. / Vliianie 1-(khlormetil)silatrana na biokhimicheskie pokazateli tkani éksperimental'noi iazvy zheludka.
Biull Eksp Biol Med
; 97(6): 658-60, 1984 Jun.
Article
em Ru
| MEDLINE
| ID: mdl-6743799
It has been demonstrated in rats with experimental gastric ulcer that 1-(chloromethyl) silatrane intensifies the development of granulation-fibrous tissue and favours optimization of the ratio of collagens and glycosaminoglycans, the main connective tissue biopolymers. Furthermore, 1-(chloromethyl) silatrane produces a more pronounced effect on hexosamine-containing glycoproteins in the ulcer tissue as compared with methyluracil and oxyferriscorbon. At the same time, judging by the time course of sialoproteins, the antiulcerous drugs, methyluracil and oxyferriscorbon, are much more effective antiinflammatory agents than 1-(chloromethyl)silatrane.
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Base de dados:
MEDLINE
Assunto principal:
Silício
/
Úlcera Gástrica
/
Compostos de Organossilício
/
Antiulcerosos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
Ru
Ano de publicação:
1984
Tipo de documento:
Article