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[Effect of 1-(chloromethyl)silatrane on biochemical indices in the tissue of experimental gastric ulcer]. / Vliianie 1-(khlormetil)silatrana na biokhimicheskie pokazateli tkani éksperimental'noi iazvy zheludka.
Biull Eksp Biol Med ; 97(6): 658-60, 1984 Jun.
Article em Ru | MEDLINE | ID: mdl-6743799
It has been demonstrated in rats with experimental gastric ulcer that 1-(chloromethyl) silatrane intensifies the development of granulation-fibrous tissue and favours optimization of the ratio of collagens and glycosaminoglycans, the main connective tissue biopolymers. Furthermore, 1-(chloromethyl) silatrane produces a more pronounced effect on hexosamine-containing glycoproteins in the ulcer tissue as compared with methyluracil and oxyferriscorbon. At the same time, judging by the time course of sialoproteins, the antiulcerous drugs, methyluracil and oxyferriscorbon, are much more effective antiinflammatory agents than 1-(chloromethyl)silatrane.
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Base de dados: MEDLINE Assunto principal: Silício / Úlcera Gástrica / Compostos de Organossilício / Antiulcerosos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: Ru Ano de publicação: 1984 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Silício / Úlcera Gástrica / Compostos de Organossilício / Antiulcerosos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: Ru Ano de publicação: 1984 Tipo de documento: Article