Prostate antigen: a marker for human prostate epithelial cells.
J Natl Cancer Inst
; 66(1): 37-42, 1981 Jan.
Article
em En
| MEDLINE
| ID: mdl-6935463
ABSTRACT
Specificity of a previously reported prostate antigen (PA) was assessed by several immunologic procedures. This antigen, restricted in distribution to the prostate gland, was detected within ductal epithelial cells. Continuous established cell lines LNCaP and PC-3 of malignant prostate origin retained the expression of PA. Tumor cells released the antigen in vitro into the culture fluid and also in vivo into the circulation of nude mice preinoculated with LNCaP cells. Prostate cells in culture also specifically accreted immunoglobulin fragments of PA antiserum.
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Base de dados:
MEDLINE
Assunto principal:
Próstata
Limite:
Animals
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Article