Penetration of intravenously administered cefoxitin into the aqueous humor of inflamed human eyes.
Am J Ophthalmol
; 94(4): 516-8, 1982 Oct.
Article
em En
| MEDLINE
| ID: mdl-6982621
ABSTRACT
Intravenous injections of cefoxitin (2-g doses for adults and 40 mg/kg of body weight doses for children) were administered 90 minutes to two hours before surgery. All nine eyes had anterior segment inflammation. Samples of aqueous humor removed during surgery showed a mean cefoxitin concentration of 6.22 micrograms/ml, almost three times the concentration reported in uninflamed eyes. The greater penetration may have been the result of a breakdown in the blood-aqueous barrier. There were no complications.
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Base de dados:
MEDLINE
Assunto principal:
Humor Aquoso
/
Uveíte
/
Cefoxitina
/
Endoftalmite
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article