Attenuation compensation in single-photon emission tomography: a comparative evaluation.
J Nucl Med
; 23(12): 1121-7, 1982 Dec.
Article
em En
| MEDLINE
| ID: mdl-6982965
ABSTRACT
Attenuation of photons in single-photon emission tomography (SPECT) makes three-dimensional reconstruction of unknown radioactivity distributions a mathematically intractable problem. Approaches to approximate SPECT reconstruction range from ignoring the effect of photon attenuation to incorporating assumed attenuation coefficients into an iterative reconstruction procedure. We have developed a computer-based simulation method to assess the relative effectiveness of attenuation compensation procedures. The method was used to study four procedures for myocardial SPECT using an infarct-avid radiopharmaceutical, Tc-99m stannous pyrophosphate. Reconstructions were evaluated by two criteria overall (sum-of-squares) accuracy, and accuracy of lesion sizing. For moderate- to high-contrast studies there were no significant differences among the reconstructions by either evaluation criterion; for low contrast ratios the iterative method produced lower sum-of-squares criterion; for low contrast ratios the iterative method produced lower sum-of-squares error. We conclude that the additional expense of the iterative method is not justified under the conditions of this study. The approach used here is a convenient tool for evaluating specific SPECT reconstruction alternatives.
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Base de dados:
MEDLINE
Assunto principal:
Tomografia Computadorizada de Emissão
/
Pirofosfato de Tecnécio Tc 99m
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article