Anamnestic response to a thymus-independent antigen, TNP-LPS in C57BL/6 and DBA/2 mice: dominance of the IgG secondary response of the C57BL/6 mice in the F1 hybrids.
Ann Immunol (Paris)
; 131C(2): 223-7, 1980.
Article
em En
| MEDLINE
| ID: mdl-6998355
ABSTRACT
The primary and secondary immune responses to a thymus-independent antigen, TNP-LPS, were investigated in C57BL/6, DBA/2 and (C57BL/6 x DBA/2)F1 mice. While there is no evidence that TNP-LPS induces immunological memory in DBA/2 mice, a definite priming effect has been observed in C57BL/6 mice. Memory is revealed by the appearrance of antibody-forming cells of the IgG isotype. The differentiation of B micron precursors into B gamma memory cells is a dominant phenotype, since it is also found in the F1 C57BL/6 x DBA/2 hybrids.
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Base de dados:
MEDLINE
Assunto principal:
Trinitrobenzenos
/
Lipopolissacarídeos
/
Técnica de Placa Hemolítica
/
Memória Imunológica
/
Nitrobenzenos
Limite:
Animals
Idioma:
En
Ano de publicação:
1980
Tipo de documento:
Article